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GSK650394A (1-10 µM) does not alter the phosphorylation of PRAS40-Ser246 in hormone-deprived cells or prevent the insulin-induced phosphorylation of this residue
gibsoni infected two dogs in chronic stage and three dogs in acute stage results in decrease in parasitemia
Smiles: CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O
PubMed PMID: 24664237
AM-0902 Catalog No.:M19855-C GSK650394A (1-10 µM) does notAM 0902 is a potent, selective transient receptor potential A1 (TRPA1) antagonist with IC50s of 71 and 131 nM for rTRPA1 and hTRPA1, respectively. Product information CAS Number: 1883711 97 4 Molecular Weight: 370. 79 Formula: C17H15ClN6O2 Chemical Name: 1 ({3 [2 (4 chlorophenyl)ethyl] 1,2,4 oxadiazol 5 yl}methyl) 7 methyl 6,7 dihydro 1H purin 6 one Smiles: CN1C=NC2N=CN(CC3=NC(CCC4C=CC(Cl)=CC=4)=NO3)C(=O)C1=2 InChiKey: AWJBWNUUODWOKQ UHFFFAOYSA N